Topics in Local Anesthetics (2024)

.6 LOCAL ANESTHETICS DrTiu Balinas converted

Local Anesthetics

Anesthesiology, 2009

Local Anesthetics – Substances with Multiple Application in Medicine

European Journal of Interdisciplinary Studies

Local anesthetics are substances which, by local action groups on the runners, cause loss of reversible a painful sensation, delimited corresponding to the application. They allow small surgery, short in duration and the endoscopic maneuvers. May be useful in soothe teething pain of short duration and in the locking of the nervous disorders in medical care. Local anesthesia is a process useful for the carrying out of surgery and of endoscopic maneuvers, to soothe teething pain in certain conditions, for depriving the temporary structures peripheral nervous control. Reversible locking of the transmission nociceptive, the set of the vegetative and with a local anesthetic at the level of the innervations peripheral nerve, roots and runners, a trunk nervous, around the components of a ganglion or coolant is cefalorahidian practice anesthesia loco-regional. Local anesthetics summary and semi-summary have multiple applications in dentistry, consulting, surgery and obstetrics, constituting...

Lidocaine: The Origin of a Modern Local Anesthetic

Anesthesiology, 2010

CLINICAL USE OF LOCAL ANESTHETICS Edited by Asadolah Saadatniaki

Formulações de Anestésicos Locais de Liberação Controlada: Aplicações Terapêuticas * Drug-Delivery Systems for Local Anesthetics: Therapeutic Applications

Current research in local anesthesia

Anesthesia progress

Local Anaesthetic Systemic Toxicity

Comprehensive Review on Structural Elucidation of Local Anesthetic and It's Adverse Effects

International Journal of Pharmaceutical Sciences Review and Research, 2023

Drugs that are classified as local anesthetics abolish the conduction of nerve impulse in afferent and efferent nerve fibers. So that any signal or stimulus are not transmitted effectively to the brain, so motor signal is not transmitted effectively to other effector organ such as muscles. Acute or Chronic pain or sensation of pain during procedures can be prevented by applying local anesthetics. Understanding about our Physiological nerve fiber and transmission of pain sensation is very much important for mechanism of action of local anesthetic. Mainly, Local anesthetics involved with nerve ending or surrounding nerve trunk and combined with the sodium ion (Na+) channel sites on the nerve membrane. They affect membrane action potential as well as depolarizing state by reducing Na+ passage through the sodium ion channel, though blocking both generation and conduction of nerve impulse. In the same way blocking both generation and conduction of sensory nerve impulse. Local anesthetics used for dental surgery; post operation pain remove. Here, we focused on review of research progress on local anesthetics, various aspect of mechanism of action, design, synthesis route, adverse or toxicological effect of new molecules (Local anesthetic).

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